First successful slider I've trained tbh. As in model description, positive weight is supposed to corrupt the character and everything else. Don't be afraid to use high weight, especially with applying other loras too, experiment with it.
It was trained on autismMix, not the pony diffusion itself.
Negative weight's effect is not very concrete but feel free to experiment with it too.
If weight is too high, your waifu will turn into a monster beyond recognition, I can imagine some people being into that too.
Also, I recommend using ADetailer with lower weight of the lora than in txt2img.